Recombinant Human DCC-interacting protein 13-alpha (APPL1) from MyBioSource.com

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Recombinant Human DCC-interacting protein 13-alpha (APPL1)

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Description

This protein has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD
MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus